R-507A
Also known as: R507A, R-507, HFC-507A, AZ-50, Genetron AZ-50
Azeotropic HFC blend for low-temperature commercial refrigeration. GWP of 3,985 is the highest of any common refrigerant — subject to accelerated phasedown pressure.
R-507A has a GWP of 3,985 — exceeding R-404A's 3,922 as the highest-GWP refrigerant in common commercial use. It faces the most severe supply constraints under AIM Act phasedown. Transitioning to R-448A or R-449A is highly recommended for cost management.
Regulatory Timeline
R-507A introduced as azeotropic low-temperature alternative to CFC-502
R-507A widely adopted for low-temperature commercial refrigeration replacing R-22 and CFC-502
AIM Act phasedown — R-507A highest-GWP refrigerant in common service use
What R-507A Is and Where It Is Used
R-507A is an azeotropic blend of R-125 (50%) and R-143a (50%), developed as a low-temperature replacement for CFC-502 and R-22 in commercial refrigeration. Its azeotropic nature means it behaves like a single-component refrigerant — no fractionation, no temperature glide — which simplifies charging and leak recovery compared to zeotropic blends.
R-507A is used primarily in low-temperature applications: blast freezers, ice cream cases, frozen food display cases, and cold storage warehouses requiring evaporating temperatures below -10°F. Its low boiling point and good low-temperature efficiency made it a preferred specification for applications where R-404A was too warm.
Despite its technical suitability, R-507A's GWP of 3,985 makes it the highest climate-impact refrigerant in common service use. This positions it at the front of AIM Act phasedown attention, and contractors and facility managers should be actively planning transitions for R-507A systems.